The #MeToo movement has given rise to #TimesUp, an initiative by 300 prominent women in the entertainment industry to fight sexual harassment and gender disparity in every workplace across the country from “movie sets to farm fields to boardrooms alike.”

“TIME’S UP is a unified call for change from women in entertainment for women everywhere,” the initiative’s website reads. “From movie sets to farm fields to boardrooms alike, we envision nationwide leadership that reflects the world in which we live.”

The initiative was announced today in an open letter of solidarity addressed primarily to working-class women and signed by hundreds of women in Hollywood, including A-list actresses Reese WitherspoonKerry WashingtonAshley JuddEva LongoriaEmma StoneAmerica Ferrera and Natalie Portman; producers Shonda Rhimes and Jill Soloway; Universal Pictures executive Donna Langley; and lawyers Nina L. Shaw and Tina Tchen.

The letter ran as a full-page ad in The New York Times and the Spanish-language newspaper La Opinion.

“We want all survivors of sexual harassment, everywhere, to be heard, to be believed, and to know that accountability is possible,” the letter reads.

The initiative includes a legal defense fund, headed by Tchen, Michelle Obama‘s former chief of staff, and backed by $13 million in donations, to help protect less privileged women from sexual misconduct and the fallout from reporting it.

It also includes an effort to increase gender parity across all industries, including Hollywood.

“The struggle for women to break in, to rise up the ranks and to simply be heard and acknowledged in male-dominated workplaces must end; time’s up on this impenetrable monopoly,” the letter reads.

By this afternoon, the #TimesUp hashtag and letter had gone viral with the help of its powerful backers.

Time’s up on silence. Time’s up on waiting. Time’s up on tolerating discrimination, harassment and abuse.  Sign the solidarity letter & donate to the @TIMESUPNW Legal Defense Fund: http://timesupnow.com 

I stand with ALL WOMEN across every industry to say  on abuse, harassment, marginalization and underrepresentation. Join me! Sign the statement of solidarity & donate to the @TIMESUPNW Legal Defense Fund: http://timesupnow.com 

No more silence. No more silencing. This is a call to action. We stand united and we fight ferocious. Tick tock, tick tock, tick—  https://twitter.com/tessathompson_x/status/947898952577413121 

“If this group of women can’t fight for a model for other women who don’t have as much power and privilege, then who can?” Rhimes told The New York Times.

According to the newspaper, Time’s Up was formed soon after producer Harvey Weinsteinwas accused by multiple women of sexual misconduct, unleashing a reckoning in Hollywood that has led to the ouster of several prominent men in the industry and given steam to the #MeToo movement of women who’ve come forward with allegations of their own harassment.

Weinstein, via his spokesman, has repeatedly denied “any allegations of nonconsensual sex.”